Essay on What is Snai2
Snai2 is a human embryonic protein which is normally referred to as SLUG. It is a zinc finger transcriptional repressor which modifies basal transcription and activator-dependent. The SLUG offers the instructions to make the snail2 protein and is found in most of the adult tissues hence it enables the normal functioning of the body cells after birth. The gene has a significant role in the development processes of the human body and inhibition of apoptosis. It is involved in the generation and migration of the neural crest cells. Snail2 attaches itself in some parts of DNA hence controls some activities of the genes. The gene encrypts a member of the Snail family of C2H2-type zinc. It has three exons which encrypt a 268-amino acid protein with a molecular mass of around 80 kDa. It is a transcription factor which has five zinc finger regions and is essential in the primary stages of cell migration from the neural tube. It normally functions by inducing epithelial-mesenchymal transition which is involved in the development and other processes of the cells. It is expressed in white adipose tissue (WAT) in human beings. A deficiency in Snai2 displays a significant deficiency in WAT size while its overexpression is marked by an increased size of WAT.